VietnamPartner Site

Site project · HIV and key populations

DRIVE-MIND II

Community mental-health care for people who inject drugs

Project overview

A psychiatric intervention integrated into community care for people who inject drugs with depression or psychotic symptoms in Hai Phong.

Objective

Determine whether a community-based psychiatric intervention can sustainably reduce HIV and HCV risk exposure, improve mental health and quality of life, and reduce harmful drug use among people who inject drugs.

Study design

Follow-up at baseline, month 6 and month 12 of participants from the DRIVE-MIND cohort with depression or psychotic symptoms, alongside 200 HIV-positive and 200 HIV-negative controls without significant psychiatric symptoms. The project also includes micro-costing and a qualitative implementation study.

Consortium

Project leadership and partner institutions

Principal investigators

  • Le Sao MaiHai Phong University of Medicine and Pharmacy
  • Laurent MichelCentre Pierre Nicole, Paris

Partner institutions

  • Hai Phong University of Medicine and Pharmacy
  • Centre Pierre Nicole, Paris
  • SCDI, Vietnam

Scientific production

Publications and communications

View the full bibliography →

  1. Trouiller P, Le SM, Hoang Thi G, Duong Thi H, Khuat Thi Hai O, Nham Thi TT, Moles JP, Laureillard D, Des Jarlais DC, Nagot N, Michel L, Pelletier-Fleury N. Micro-costing analysis of a community-based psychiatric intervention among people who inject drugs in Haiphong, Vietnam. Frontiers in Psychiatry. 2025;16:1676340. doi: 10.3389/fpsyt.2025.1676340.

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  2. Nguyen Thu Trang, Nguyen Huu Anh, Han Dinh Hoe, Dinh Thi Thanh Thuy, Le Minh Giang, Le Sao Mai, Duong Thi Huong, Hoang Thi Giang, Philippe Trouiller, Laurent Michel. Strained patient-provider relationship, unmotivated workforce, financial constraints, and stigma: Multiple challenges in integrating mental health care within Vietnam's methadone clinics. Journal of Ethnicity in Substance Abuse. 2025. doi: 10.1080/15332640.2025.2513484.

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  3. Moulis L, Le SM, Hai VV, et al. Gender, homelessness, hospitalization and methamphetamine use fuel depression among people who inject drugs: implications for innovative prevention and care strategies. Frontiers in Psychiatry. 2023;14:1233844. doi: 10.3389/fpsyt.2023.1233844.

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  4. Le SM, Trouiller P, Duong TH, et al.; DRIVE Study Team. Development and assessment of a community-based screening tool for mental health disorders among people who inject drugs. Drug and Alcohol Review. 2022;41(3):697–705. doi: 10.1111/dar.13402.

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  5. Michel L, Le SM, Thi GH, et al.; DRIVE Study Team. Assessment of a psychiatric intervention at community level for people who inject drugs in a low-middle income country: the DRIVE-Mind cohort study in Hai Phong, Viet Nam. The Lancet Regional Health – Western Pacific. 2021;18:100337. doi: 10.1016/j.lanwpc.2021.100337.

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